Hi Xgodz,
Welcome to the forums. Thank you for reporting your experience of this issue and the details of your gameplay setup.
I just recently updated the post HawkGirl mentioned (thanks HawkGirl!) - [Known Issue][PS4/XB1] Loss of interactions
The team believe they have found the cause of the issue and are now working to resolve it. I will update the above post if I recieve any more information.