I have unlocked all 4 tool belt pouches by crafting. I bind tools to the belt keys successfully. I have bound pouches 1-4. When I save and exit the game, then start the game up again later and load my only save slot - the hotkeys are no longer bound. My items are still present, but I have to re-bind the items. I am able to use the hotkeys after binding them throughout my play time till I save and exit.
No custom Islands.
Start the game and load my save slot
Press 1 to equip (previously mapped knife)
-Have you tried reloading your save, game or PC? Yes
-Have tried reinstalling the game? No